3d Functional Modeling of Dbs Efficacy and Development of Analytical Tools to Explore Functional Stn

iv Acknowledgments I would like to express my gratitude to my adviser, Dr. Ou Bai for his continuous support throughout in my study and research. His guidance and encouragement have helped me pursuing this exciting line of research. Throughout the entire project he has encouraged me to develop independent thinking and research skills. I am extremely thankful to Dr. Kathryn Holloway for giving me the opportunity to work on this research and providing the clinical data for analysis. Her in-depth knowledge and logical way of thinking has been of great help to me. Her extensive discussions around my work and constructive comments have been very helpful throughout this project. I would like to thank Dr. V. Ramakrishnan, whose help, suggestions, patience and encouragement has helped me at all times during this research project. I would also like to thank all my committee members, Dr. and Dr. Din-Yu Fei for all the guidance and support throughout this project. Their detailed review, constructive criticism and excellent advice have helped me immensely in completion of my thesis project and improving my skills for technical writing.